although / though / even if / even though: aunque
for all (that): a pesar de que
much as: a pesar de lo mucho que, por mucho que
however + adjetivo: por muy + adjetivo que
no matter how + adjetivo: no importa lo + adjetivo que
whatever: sea lo que sea lo que
whereas / while / whilst: mientras que

in spite of / despite: a pesar de + sutantivo
in spite of / despite: a pesar de + verbo en -ing
in spite of the fact (that) / despite the fact (that): a pesar de que + oración

Despite / In spite of the rain, he goes out.
(A pesar de la lluvia, sale.)
Despite / In spite of being raining, he goes out.
(A pesar de estar lloviendo, sale.)
Despite the fact (that) / In spite of the fact (that) it is raining, he goes out.
(A pesar de que está lloviendo, sale.)